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Soy - the Antinutrient

Soy, much vaunted by nutritionists and vegetarians, is actually a very harmful food, especially for growing children. Soy is a potent antinutrient, that is, it prevents the absorption of many vitamins and minerals, including iron, calcium, and zinc through its high levels of phytic acid, and vitamins A and D through its anti-enzymatic activity. Furthermore, soy contains trypsin and papain inhibitors [1]. Trypsin and papain are enzymes which digest protein , and so although soy contains protein, and tofu has calcium (which is added during the processing), very little is being absorbed.

Many people consume soy products because of its alleged anti-carcinogenic properties, especially with respect to cancer of the prostate and the breast. Well, sorry to disappoint you, but two large scale studies found no protective effect of soy on prostate cancer.

With respect to breast cancer, there is some weak evidence in the form of correlation studies. One study is especially weak. It showed that women whose husbands ate less beef and wieners and more miso (but not tofu) had less incidence of breast cancer. This assumes that the women ate the same things as the men, which is a huge assumption to make. (All of you reading this ask yourselves if you and your spouses or significant others eat the same foods all of the time).

Another study showed an inverse correlation between consumption of soybean paste soup and breast cancer. Again, this is weak evidence in it of itself because women who eat soy bean paste soup might also be more likely to eat vegetables or fruit, eat less processed foods or Omega 6 fats or smoke less, or a million other factors that one cannot possibly take into account [2]. Simply copying part of another diet based on speculation and weak correlation studies is quite frankly irresponsible. In fact, a few studies have shown increased soy consumption provides no protective effect or an unclear effect on breast and colon cancer or cancer in general [3], [4], [5], and one study showed an increase in breast tissue proliferation after supplementation with soy protein [6].

Thus, the bottom line is that soy seems to have no protective effect on prostate cancer, and probably cancer in general. Although it might protect against breast cancer, it probably doesn't, and plus, there are many other things women can do to lower their risk, such as exercise, not smoke, and follow a low carb diet. That's right. Sugar has the highest correlation to breast cancer from any food group, and that is attributed to insulin [7].

Another interesting finding is that cerebrovascular disease is directly correlated with consumption of plant proteins, excluding those from cereals. In fact, Japanese men, who consume some of the highest amount of plant proteins in the world, often in the form of soy, also are world leaders in stroke mortality. Again, correlation obviously does not mean causation, but a possible explanation is proposed. Soy contains large amounts of phytoestrogens, compounds in plants which mimic estrogen. In men, this exogenous estrogen might lead to damaged cerebral arteries [8]. To be fair though, it is not completely known and further research is of course needed to confirm this.

Soy is also a potent food allergen and as such can weaken the immune system, which is busy getting rid of the soy proteins in the blood and thus is more susceptible to bacterial or viral infection.

Finally (I bet you're going to love this one), soy consumption in pregnant women has been linked to a five-fold increase in hypospadias, which is a penile defect, possbly because of the high phytoestrogen content in soybeans [9].

References

  1. Seely, Stephen, et al. Diet Related Diseases - The Modern Epidemic.The AVI publishing company. Westport, Connecticut. 1985. pp. 43-70
  2. Shils, Maurice E. Olson, James A. Shike, Moshe. Ross, Catherine A.(eds). Modern Nutrition in Health and Disease. Williams and Wilkins. Baltimore, Maryland. 1999. pg. 1276
  3. Messina, M. J. "Legumes and soybeans: overview of their nutritional profiles." American Journal of Clinical Nutrition. Sep. 1999. 70(3 Suppl):439S-450S
  4. Messina, M. and M. Bennick. "Soyfods, isoflavones, and risk of colonic cancer: a review of the in vitro and in vivo data." Baillieres Clinical Endocrinology & Metabolism. Dec. 1998. 12(4):707-28
  5. Anderson, J. W., Smith, B. M., and C. S. Washnock. "Cardiovascular and renal benefits of dry bean and soybean intake." American Journal of Clinical Nutrition. Sep. 1999. 70(3 Suppl):464S-474S
  6. McMichael-Phillips, D. F., et al. "Effects of soy-protein supplementation on epithelial proliferation in the histologically normal human breast." American Journal of Clinical Nutrition. Dec. 1998. 68(6 Suppl):1431S-1435S
  7. Seely, Stephen, et al. Diet Related Diseases - The Modern Epidemic.The AVI publishing company. Westport, Connecticut. 1985. pp. 190-200
  8. Seely, S. "Diet and cerebrovascular disease: search for linkages." Medical Hypotheses. Nov. 1982. 9(5)509-15
  9. BJU International 2000;85:107-113.

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